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Duke study identifies SERINC2 as potential target for preventing brain metastasis

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A peer-reviewed study from Mikhail Nikiforov's team at Duke University, published in Cell Reports in 2026, identifies SERINC2 as a potential intervention target for preventing brain metastasis. The findings suggest a new avenue for stopping cancer from spreading to the brain, a major cause of morbidity and mortality in patients with advanced disease. The work is early-stage laboratory research rather than a clinical result, and no therapeutic approach targeting SERINC2 has yet entered development or testing in patients. How the finding might translate into preventive treatment, and in which cancer types it would apply, remains open.

Written by a model from the reports · updated 4 hours ago

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Oct 27
  1. medicalxpress.comPick
    Pathology research identifies potential new target for preventing brain metastasis

    A peer-reviewed study by Mikhail Nikiforov's team at Duke University, published in Cell Reports (2026), identifies SERINC2 as a potential intervention target for preventing brain metastasis.

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