medicalxpress.com· Medical Xpress - Cancer·· 19 hours agoPickScore65
Pathology research identifies potential new target for preventing brain metastasis
In brief
A peer-reviewed study by Mikhail Nikiforov's team at Duke University, published in Cell Reports (2026), identifies SERINC2 as a potential intervention target for preventing brain metastasis.
Why it matters
The paper presents the mechanism by which SERINC2 activates AXL through phosphatidylserine remodeling to promote brain metastasis, with animal models supporting its functional role.
Source: medicalxpress.com · medicalxpress.com