Needle-Free mRNA Vaccine Shows Protection Against COVID and Flu in Lab Study
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A Rutgers team working with Japanese institutions has shown that a high-pressure liquid jet can deliver unencapsulated mRNA directly into the skin, offering a needle-free alternative to conventional injection. In mice, the approach also demonstrated that combining aluminum phosphate and CpG as adjuvants strengthens both antibody and cellular immune responses. The work points toward a single platform that could protect against both COVID and flu without needles, which matters for vaccines that rely on cold chains and lipid encapsulation. The findings are from a laboratory study reported on 2026-10-23; no human trials have been announced, and questions of efficacy, safety and manufacturability in people are still open.
Written by a model from the reports · updated 2 hours ago
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- medicalxpress.comPickLab study shows needle-free mRNA vaccine protects against COVID and flu
A Rutgers team working with Japanese institutions found that a high-pressure liquid jet delivers unencapsulated mRNA into the skin, and combining aluminum phosphate and CpG strengthens antibody and cellular responses in mice.
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