medicalxpress.com· Medical Xpress - Medications·· 20 hours agoPickScore66
Lab study shows needle-free mRNA vaccine protects against COVID and flu
In brief
A Rutgers team working with Japanese institutions found that a high-pressure liquid jet delivers unencapsulated mRNA into the skin, and combining aluminum phosphate and CpG strengthens antibody and cellular responses in mice.
Why it matters
The study provides a naked-mRNA intradermal jet delivery route with two adjuvants, using a lipid particle formulation as an inflammation comparator.
Source: medicalxpress.com · medicalxpress.com