Nurullah İlhan,MD· @drnurullahilhan · X·· 21 hours agoScore70
Body · original
FINER/MA.40: prior PFS success, no significant OS benefit.
ER+/HER2− metastatic breast cancer after CDK4/6i + AI:
Ipatasertib + fulvestrant vs placebo + fulvestrant
OS: 26.68 vs 25.76 months
HR 0.97; P=0.83
AKT-altered subgroup OS also not significant.
#FINER #ESMO2026 #BCSM
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Conference abstracts
LBA14matched by Proffered paper 2: Breast cancer, early and advanced stage
A double-blind placebo controlled randomized phase III trial of fulvestrant and ipatasertib as treatment for HER-2 negative and estrogen receptor positive (ER+) metastatic breast cancer (MBC): Overall survival results of the CCTG/BCT MA.40/
https://esmocongress.esmo.orgSource: Nurullah İlhan,MD · x.com