Medical Xpress· Medical Xpress - Cancer·· 1 day agoPickScore58
New study identifies immune trigger behind radiation-related lung damage
In brief
A City of Hope team published a preclinical study in Nature Communications showing that radiation raises IFN-beta levels, converting protective ILC2 cells into pro-inflammatory ILC1 cells, thereby driving damage to healthy lung tissue.
Why it matters
The study presents the specific immune mechanism of IFN-beta driving ILC2-to-ILC1 conversion and mouse evidence that blocking the pathway reduces lung injury.
Source: Medical Xpress · medicalxpress.com