doi.org· The Journal of cell biology·· 1 day agoPickScore72
Adhesion integrity activates mechanosensitive proliferative signaling
In brief
Experiments in MCF10A cells show that adhesion integrity maintained by P-cadherin and FAK enhances Src-dependent myosin II and ERK activation, and strengthens ERK and SRF signaling to support cell proliferation.
Why it matters
MCF10A cells and a Drosophila model show that P-cadherin- and FAK-maintained adhesion integrity enhances Src-dependent proliferative signaling.
Source: doi.org · doi.org