Lung cancer: perioperative IO and KRAS NSCLC
Sherlock-Lung’s 1,209 whole genomes: EGFR more often in never-smokers, KRAS more often in smokers.
Research presented by Mariana Do Carmo @yalepathology shows tumor suppressor gene loss plays a major role in how EGFR-mutant #lungcancer grows and responds to therapy. Certain gene losses can accelerate tumor growth or drive resistance to EGFR inhibitors. #AACR26 @AACR @SmilowCancer @OncoAlert @StockhammerPaul
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