Immunotherapy: CAR-T in solid tumors, mRNA vaccines, TCR-T
Personalized mRNA vaccines are simpler on paper: sequence the tumor, build a shot, add a PD-L1 antibody and chemotherapy. MSK’s autogene cevumeran showed responders living more than three times as long as non-responders.
An experimental, personalized vaccine using #mRNA to prevent #pancreaticcancer from returning after surgery continues to show promise in a small, 16-person patient group.
New results from a phase 1 clinical trial, being presented at #AACR26, show that nearly 90% of people
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Tong Xie, Jian Zhang, Yanchun Meng, Xu Jia, Yue Fan, Li Wang, Jennifer Yang, Sandra Zeng, Hongxia Wang, Lin Shen
Read the abstract →Source: Memorial Sloan Kettering Cancer Center · x.com