mp.weixin.qq.com·· 3 hours agoPickScore85
ESMO 2026 Chinese Orals: Dual TKI Improves MET-Amplified Resistance, CS2009 and Ivonescimab Report NSCLC and Thymic Carcinoma Data
In brief
Three Chinese-led oral presentations at ESMO 2026 updated data on MET-amplification resistance, NSCLC, and thymic carcinoma. A dual-TKI regimen significantly improved PFS in a randomized phase 3 study: NCT06110663 randomized 314 patients, with IRC-assessed mPFS of 6.2 vs 4.4 months, HR 0.601, P<0.001. CS2009 showed a preliminary ORR/DCR of 81.3%/100% in the evaluable first-line PD-L1 TPS≥50% population.
Why it matters
All three abstracts report sample size, efficacy, and safety data, and the randomized phase 3 study used platinum chemotherapy as a control.
Source: mp.weixin.qq.com · mp.weixin.qq.com