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Yale Cancer Center· @YaleCancer · X·· 2026-04-20Score60

#BREASTCANCER

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Next-generation ADCs: payload innovation

T-DXd is already rewriting the first-line standard.

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@jsnibbor
shares how the use of spatial transcriptomics reveals response vs resistance to T-DXd in metastatic #breastcancer #MBC. Responders show stronger hormone & cell-adhesion signals, while resistance is linked to protein breakdown & more suppressive tumor features. #AACR26

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Source: Yale Cancer Center · x.com

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