x.com· @ · X·· 2026-04-22Score60
Reading
Next-generation ADCs: payload innovation
AVA6103 / pan-RAS ADC · Tricomplex pan-RAS as payload
Body
Great News! “Presentation of additional analyses from FAP-Exd (AVA6103) study shows robust activity in PDX models with low FAP expression and more favorable kinetic profile compared to the marketed antibody-drug conjugate (ADC) Enhertu.” #AVCT #AACR26 https://t.co/emOsW1aCrX
Heat 52 · 45 likes · 1 reply · 6 reposts
Conference abstracts
5846matched by 代号 AVA6103
AVA6103 is a FAP-enabled pre|CISION®peptide-drug conjugate delivering sustained release of exatecan in the tumor microenvironment with potent antitumor activityCurtis Rink, Tom Clough, Ellen Watts, Folake Orafidiya, Marine Houée, Sophie Brown, Victoria Juskaite, Gezim Lahu, Ruairidh Edwards, Karen Campbell, Dave Liebowitz, David Jones, Francis Wilson, Michelle Morrow
Read the abstract →Source: x.com · x.com