x.com· @ · X·· 2026-04-22Score60
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Platform layer: molecular glues, spatial omics, AI
FHD-909 / MRT-55811 / MR-2088 · Epigenetic / ULK tool molecules on the floor
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Excellent talk by Ralph Tiedt @MonteRosaTx about drugging cyclin E1 with molecular glue degraders #AACR26: MRT-55811 shows high selectivity, noteworthy co-degradation of CDK2 (via quaternary complex induction), impressive cellular selectivity & differences to CDK2 inhibitors. https://t.co/XCzvJTWl9x
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