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AACR Annual Meeting 2026

April 17–22, 2026 · San Diego · 2418 items

← Lung cancer: perioperative IO and KRAS NSCLC

adebrelimab

★★★Clinical trial

11 people · 12 posts · 4 abstracts

Heat trend for this story

Heat now 1·Peak in the comparable set 1 (Oct 23 20:00)·Change over 24h in the comparable set –·Participants now 1

Participants counted1
00.250.50.751
Heat over time
00.250.50.751Oct23Oct23Oct24Oct24

A Chinese PD-L1 antibody (adebrelimab) sat down at that table with EFS data.

Records
Drug / trialReadoutSetting
adebrelimabadebrelimab#NSCLCPerioperative EFS HR 0.52Resectable NSCLC
Other cases in this chapter
Evidence

Perioperative adebrelimab (A) plus chemotherapy (chemo) in resectable stage II-III NSCLC: Phase 3 EFS interim analysis (IA) and molecular residual disease (MRD) analysis

Yi-Long Wu, Wen-Zhao Zhong, Li-Xu Yan, Keneng Chen, Wanpu Yan, Yongzhong Luo, Wenxiang Wang, Wenqun Xing, Xiaolong Yan, Lin Wu, Feng Yao, Dongsheng Yue, Naiquan Mao, Yu Qi, Bentong Yu, Jianji Guo, Jindan Kai, Yuejun Chen, Hui Wang, Qin Zhang, Lunxu Liu, Honghai Wang, Yuanyuan Ji, Yongtao Han, Yongxiang Song, Jianjun Xu, Wei Guo, Hongxu Liu, Di Ge, Hecheng Li, XiuJuan Qu, Jifang Yao, Junfeng Liu, Tingyan Zhong, Yanhua Huang, Li Song, Wei Shi

Combination of risvutatug rezetecan and adebrelimab in previously treated advanced nsq-NSCLC without actionable genomic alterations: Results from ARTEMIS-101, a phase 1 study

Hua Zhong, Haifeng Liu, Wei Zheng, Linlin Wang, Baogang Liu, Fangling Ning, Yongzhong Luo, Qiming Wang, Weiliang Zhu, Jianying Zhou, Qingwei Zhao, Ruoyu Wang, Xiang Li, Juan Li, Runbo Zhong, Yizhou Jin, Xiangru Mao, Jing Wang, Qingyuan Liu, Xiaoqing Zhang

CT239

Neoadjuvant adebrelimab plus chemotherapy in untreated locally advanced head and neck squamous cell carcinoma: Efficacy and biomarker insights from a single-arm phase II trial

Ruihua Fang, Bixue Huang, Lin Chen, Rongjian Zhan, Yicheng Deng, Weiping Wen, Wenbin Lei

SHR-A1811 ± adebrelimab as first-line (1L) treatment for advanced HER2-mutant NSCLC: A randomized phase 2 cohort from a phase 1b/2 study

Shun Lu, Zhengbo Song, Ziming Li, Haiyong Wang, Yan Yu, Qitao Yu, Shaozhang Zhou, Zhiyong He, Yan Wang, Yiping Zhang, Songyan Han, Rui Meng, Guoqun Zhang, Longhua Sun, Xueqin Chen, Yong Mao, Yongsheng Li, Yongzhong Luo, Kangsheng Gu, Xuhong Min, Bo Jin, Runxiang Yang, Yanqiu Zhao, Liqiang Zhong, Jun Wang, Zhiguo Zhou, Chengzhi Zhou, Kaijun Zhang, Xiaotong Li, Xinjing Ma, Liju Zong, You Li

Floor
  1. Cancer Cell

    Chemotherapy-free phase 1/2 trial of HRS-4642 plus adebrelimab in previously treated metastatic KRAS G12D-mutant pancreatic cancer

    In the first clinical study of HRS-4642 combined with adebrelimab in previously treated patients with metastatic KRAS G12D-mutant pancreatic cancer, the chemotherapy-free regimen showed manageable safety and preliminary antitumor activity.

    Why it matters: First clinical study of a chemotherapy-free combination in this patient population.

CBACBA Frontier Insights (CFI)Chinese Biopharmaceutical Association (CBA)www.cba-usa.org