Cell· Huaqing Deng, Guowen Jia, Qin Yang, Lin Zhao, Ping Li, Min Ling, Jiaqi Fan, Yingfeng Tu, Xin Yong, Ying Lai, Zhaoming Su, Da Jia·· 4 天前评分44
Cargo crosslinking nucleates AP-1 lattice formation
Cargo crosslinking nucleates AP-1 lattice formation
导读
冷冻电镜揭示，含有串联分选基序的货物可直接通过桥接AP-1复合体来促进高阶衔接蛋白组装。这一机制支持了高效的膜泡运输，并在斑马鱼模型中证实对神经元发育至关重要。
来源：Cell · cell.com