Children Conceived Through Assisted Reproduction Show Higher Cancer Risk in Danish Cohort
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A nationwide Danish cohort study published in JAMA compared cancer incidence in children conceived with assisted reproductive technology (ART) against naturally conceived children. The ART group had a cancer incidence of 23.6 cases per 100,000 person-years, versus 18.3 per 100,000 in the non-ART group, corresponding to a hazard ratio of 1.26 (95% CI 1.07-1.48). The finding indicates a modestly elevated risk of childhood cancer associated with ART conception. The study's confidence interval excludes 1.0, but the underlying mechanisms, whether the excess risk stems from the technology itself, underlying parental infertility, or other factors, and how the finding generalizes beyond the Danish population, remain open questions.
Written by a model from the reports · updated 3 hours ago
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- JAMAChildhood Cancer Risk After Assisted Reproductive Technology.
A nationwide Danish cohort found a cancer incidence of 23.6 cases per 100,000 person-years in children conceived with assisted reproductive technology, compared with 18.3 per 100,000 in the non-ART group (HR 1.26, 95% CI 1.07-1.48).
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