JAMA Trial Compares FiO2 0.30 Versus Air for Preterm Infants at Birth
Start here
A cluster randomized clinical trial published in JAMA on October 20, 2026 compares the safety and efficacy of starting respiratory support at birth with FiO2 0.30 versus 0.21 (air) in infants born at 32 to 35 weeks' gestation. Moderate- to late-preterm babies are a large population where the optimal initial oxygen concentration for resuscitation has long been uncertain, and this trial addresses that question directly. The publication currently describes the study design; outcome results have not yet been reported in the available material, so whether FiO2 0.30 or air proves safer or more effective remains open, as do implications for delivery-room practice guidelines.
Written by a model from the reports · updated 3 hours ago
Coverage timeline
Follow the coverage to see the different angles.
- JAMA NetworkPickOxygen vs Air at Birth for Moderate- to Late-Preterm Infants
JAMA published a cluster randomized clinical trial comparing the safety and efficacy of starting respiratory support at FiO2 0.30 versus 0.21 (air) in infants born at 32 to 35 weeks' gestation. The abstract describes the study design; specific outcome data were not provided in the feed text.
Coverage and heat for this story
Reports so far 3·Heat now 6·Peak heat 10 (Oct 20 08:00)·Reports, 24h +3
Two panels, same clock (pointer stays in sync): top is cumulative editorial reports — only rises; last point = All reports; slope = new reports that hour. Bottom is Live-board heatIndex — 7-day participants with a 24-hour half-life, so it can fall when talk cools.