Xiamen University Team Identifies Cuproptosis Effector Protein in Cell, Acetylation Boosts Copper Binding
Start here
A Xiamen University team publishing in Cell identified an effector protein of cuproptosis and found that acetylation enhances the protein's binding of copper ions. Cuproptosis, named in 2022, is a form of programmed cell death distinct from apoptosis, pyroptosis and ferroptosis; excess copper targets lipoylated mitochondrial proteins, triggering protein aggregation and degradation of iron-sulfur cluster proteins.
Excerpted from WeChat
Coverage timeline
Follow the coverage to see the different angles.
- WeChatPickXiamen University Team Identifies Cuproptosis Effector Protein in Cell, Acetylation Boosts Copper Binding
A Xiamen University team publishing in Cell identified an effector protein of cuproptosis and found that acetylation enhances the protein's binding of copper ions. Cuproptosis, named in 2022, is a form of programmed cell death distinct from apoptosis, pyroptosis and ferroptosis; excess copper targets lipoylated mitochondrial proteins, triggering protein aggregation and degradation of iron-sulfur cluster proteins.
Coverage and heat for this story
Reports so far 1·Heat now 8·Peak heat 10 (Oct 19 17:00)·Reports, 24h +1
Two panels, same clock (pointer stays in sync): top is cumulative editorial reports — only rises; last point = All reports; slope = new reports that hour. Bottom is Live-board heatIndex — 7-day participants with a 24-hour half-life, so it can fall when talk cools.