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Roche licenses Zymeworks' trispecific T cell engager ZW209 in up-to-$813M lung cancer deal

1 report1 sourceupdated 4 hours ago

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Roche has paid Zymeworks $55 million upfront for an exclusive global license to ZW209, a trispecific T cell engager it plans to develop for lung cancer. The deal could reach $813 million in total. A further $40 million is due if ZW209 enters Phase 1b testing, and Zymeworks is eligible for up to $718 million in development, commercial and sales milestones, plus high-single-digit to mid-teen royalties on future net sales. The partnership was announced on October 23, 2026; no clinical results for ZW209 under Roche have been reported yet.

Written by a model from the reports · updated 3 hours ago

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Oct 23
  1. biospace.comPick
    Roche bets up to $813M on Zymeworks’ lung cancer trispecific T cell engager

    Roche is paying a $55 million upfront for an exclusive global license to Zymeworks' ZW209 and plans to develop it for lung cancer, in a deal worth up to $813 million. If ZW209 enters Phase 1b testing, Roche will pay an additional $40 million, plus up to $718 million in development, commercial and sales milestones. Zymeworks is eligible for high-single-digit to mid-teen royalties on future net sales.

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