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Six-Month Probiotic Powder Improved Memory Scores in Older Adults with Early Memory Problems

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A small placebo-controlled trial found that a daily probiotic powder taken for six months improved memory and thinking scores in older adults with early memory problems, and lowered a blood marker linked to Alzheimer's disease. The researchers themselves caution the findings are early-stage, but say the trial adds to growing evidence that gut health influences brain function. The trial was placebo-controlled, which strengthens the signal compared with observational reports, but its small size means the results cannot yet support clinical recommendations. Open questions include whether the cognitive and blood-marker benefits hold up in larger trials, whether they translate to reduced risk of progression toward Alzheimer's, and which components of the probiotic mixture drive the effect.

Written by a model from the reports · updated 4 hours ago

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Oct 20
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    A daily probiotic powder taken for six months improved memory and thinking scores in older adults with early memory problems, and lowered a blood marker linked to Alzheimer's, in a small placebo-controlled trial. Researchers say it's early, but it adds to evidence that gut health affects your brain.

    A 24-week double-blind randomized controlled trial of 87 participants from the Korean GARD cohort found that the three-strain probiotic KL-P301, containing Bifidobacterium longum subsp. animalis, Limosilactobacillus fermentum, and Levilactobacillus brevis, significantly reduced plasma pTau181 (p<0.001) and improved CDR scores in older adults with early memory problems.

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CBACBA Frontier Insights (CFI)Chinese Biopharmaceutical Association (CBA)www.cba-usa.org