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MHRA authorises plozasiran for familial chylomicronaemia syndrome in UK adults

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The UK's MHRA has authorised plozasiran, marketed as Redemplo, for adults with familial chylomicronaemia syndrome, a rare genetic disorder of triglyceride metabolism. The authorisation, granted on 19 October 2026, marks the arrival of a targeted RNA-based therapeutic option for a condition that has historically been managed with strict dietary fat restriction. As of now, the approval stands as a UK regulatory decision; questions that remain open include how quickly patients will access the drug in practice, its uptake across the NHS, and whether other regulators follow the MHRA's lead.

Written by a model from the reports · updated 3 hours ago

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Oct 20
  1. gov.ukPick
    MHRA authorises plozasiran (Redemplo) for adults with familial chylomicronaemia syndrome

    The UK MHRA authorised plozasiran (Redemplo) on 19 October 2026 for adults with familial chylomicronaemia syndrome. Original link: https://gov.uk/government/news/mhra-authorises-plozasiran-redemplo-for-adults-with-familial-chylomicronaemia-syndrome

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