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Prof. Dr. Ahmet Dirican· @dr_dirican · X·· 2 days agoScore45

#MRNA

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Cancer vaccines: After 100 years of setbacks, are we finally getting closer?

My key takeaways from #ESMO2026:

• Personalized mRNA vaccines may generate durable T-cell immunity, even in low-TMB tumors.
• Promising signals in pancreatic cancer and melanoma.
• Phase III validation and broader access remain critical.

The next frontier in precision oncology?
@myESMO #esmo2026 #mrna #cancer

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Conference abstracts
LBA1matched by Presidential Symposium I

INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)

https://esmocongress.esmo.org

Source: Prof. Dr. Ahmet Dirican · x.com

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