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Erika Hamilton, MD, FASCO· @ErikaHamilton9 · X·· 2 days agoScore70

EGFR

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#PANKUBreast01

Ph III results for iza bren (bispecific EGFR/HER3 ADC) vs TPC chemo, in previously treated HR +/HER- MBC

🔹mPFS: 4.0 vs. 8.1 mo, HR 0.41
🔹 ORR: 20% vs 40%
🔹 DoR: 4.2 vs. 6.9 mo
🔹 ILD: only 1.1% & all grade 1/2

#ESMO26 #ESMOAmbassadors

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Conference abstracts
2700ROmatched by Rapid oral 1: NSCLC, metastatic

Improving prevention of moderate to severe dermatologic adverse events in EGFR-mutant advanced NSCLC treated with first-line (1L) subcutaneous (SC) amivantamab + lazertinib: First results from a new COCOON cohort

https://esmocongress.esmo.org
NCT06110663NCT06110663matched by - **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy

- **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy

https://esmocongress.esmo.org

Source: Erika Hamilton, MD, FASCO · x.com

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