Penn Medicine· @PennMedicine · X·· 2026-04-21Score60
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Immunotherapy: CAR-T in solid tumors, mRNA vaccines, TCR-T
CAR-PRISM’s universal MRD negativity happened in a window of healthier T cells and lower burden; solid tumors do not have that window yet.
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Janos L. Tanyi, MD, PhD, shared new #CART research at #AACR26 today. The first-of-its-kind Phase I clinical trial uses a KIR-CAR modeled after natural killer cells and designed to limit T cell exhaustion.
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Source: Penn Medicine · x.com