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First Telomere-to-Telomere Complete Genome of the Common Marmoset Published in Cell
In brief
Cell has published the first telomere-to-telomere (T2T) complete genome of the common marmoset (Callithrix jacchus), filling gaps in the previous reference sequence across highly repetitive regions including centromeres, telomeres, pericentromeric short arms, sex chromosomes, and the MHC immune region. The resource provides a more complete reference for genetic analysis of models of neuropsychiatric disorders such as Alzheimer's disease and for primate comparative genomics.
Why it matters
Provides an end-to-end complete reference sequence that enables genetic analysis previously blocked by unresolved repetitive regions in neurodegenerative disease and primate evolution research.
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