Skip to content
Ingo Hartung· @HartungIngo · X·· 2026-04-21Score60
Body · original

Brian Liau
@Harvard
about the stunning finding that the molecule UM171 & mutations found in human cancers both induce glueing of KBTBD4 to HDAC1/2 leading to CoREST degradation. Leading to the idea of utilizing deep mutational scanning to identify glueable protein pairs. #AACR26

Heat 66 · 58 likes · 1 reply · 7 reposts

Source: Ingo Hartung · x.com

CBACBA Frontier Insights (CFI)Chinese Biopharmaceutical Association (CBA)www.cba-usa.org