顶刊论文（社媒热度）· Nat Med·· 1 day agoPickScore73
Molecular predictors of minimal residual disease in newly diagnosed multiple myeloma treated with quadruplet therapy.
In brief
A Nature Medicine study performed multiomic analysis of 423 patients with newly diagnosed multiple myeloma and built a molecular prediction model for MRD status after Isa-KRd quadruplet induction, achieving an AUC of 0.77.
Why it matters
Multiomic classification linked to Isa-KRd efficacy; random forest model with AUC 0.77 can guide early treatment decisions and was validated across multiple cohorts.
Source: 顶刊论文（社媒热度）