ProfSiowMingLee· @ProfSiowMingLee · X·· 15 hours agoScore70
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Following up on our commentary on global validation for Chinese CPIs:
Presented at #ESMO26: The US randomized ASTRIDE study marks the first bridging trial to validate a Chinese anti-PD-1 CPI (serplulimab) in a US population! 🇺🇸
Key findings vs standard atezolizumab + chemo:
🔹 mOS: 12.4 vs 10.2 mo (HR 0.82)
🔹 24-mo OS: 32.2% vs 17.6%
🔹 Safety: Comparable profiles
A step forward in confirming that data from trials like ASTRUM-005 successfully translates to Western cohorts! 🌍 #ESSCLC #LungCancer #IO
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