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Nurullah İlhan,MD· @drnurullahilhan · X·· 19 hours agoScore70

DASL-HICAP

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DASL-HiCaP: primary MFS endpoint met.

In trial-defined very high-risk nonmetastatic prostate cancer, adding darolutamide to ADT + RT improved conventional-imaging MFS:
4-year MFS: 95% vs 88%
HR 0.42; P=0.0001

OS not significant yet.

#DASLHiCaP #ESMO2026 #ProstateCancer

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Conference abstracts
LBA1matched by Presidential Symposium I

INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)

https://esmocongress.esmo.org
LBA2matched by Presidential Symposium I

Perioperative durvalumab with or without tremelimumab plus neoadjuvant enfortumab vedotin in muscle-invasive bladder cancer: Results from the phase 3 VOLGA trial

https://esmocongress.esmo.org
LBA3matched by Presidential Symposium I

Tarlatamab plus durvalumab (durva) vs durva as 1L maintenance (1LM) therapy following durva, platinum, and etoposide (1L durva + EP) in extensive-stage small cell lung cancer (ES-SCLC): Primary analysis of the phase 3 DeLLphi-305 trial

https://esmocongress.esmo.org
LBA4matched by Presidential Symposium I

Darolutamide with androgen deprivation therapy (ADT) and definitive or salvage locoregional radiation therapy (RT) for localised, very high-risk prostate cancer: Interim analysis of an international, placebo-controlled, randomised phase 3 t

https://esmocongress.esmo.org

Source: Nurullah İlhan,MD · x.com

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