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Sara Tolaney· @stolaney1 · X·· 2 days agoScore90

HORIZON-BREAST06

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HORIZON-Breast06: Trastuzumab rezetecan in metastatic HER2low breast cancer
n=551
PFS chemo-naive: 16.6 vs 6.8 mo HR 0.25
PFS consistent in HR+ vs HR- (HR 0.34 and HR 0.24)
OS immature
ILD 2.5%

@OncoAlert #ESMO2026

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Conference abstracts
LBA13matched by Proffered paper 1: Breast cancer, early and advanced stage

Trastuzumab rezetecan (SHR-A1811) in HER2-low advanced breast cancer (BC): A randomized, phase 3 study (HORIZON-Breast06)

https://esmocongress.esmo.org

Source: Sara Tolaney · x.com

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