Ingo Hartung· @HartungIngo · X·· 2026-04-21Score60
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Platform layer: molecular glues, spatial omics, AI
New Drugs on the Horizon put AMX-883 in a first-disclosure seat.
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Martin Pass from Amphista Tx disclosing AMX-883, a DCAF16 hijacking oral “targeted glue” of BRD9 to induce differentiation of AML cells. An impressively potent & fast degrader. The targeted protein degradation field starts to move beyond CRBN & VHL for E3 hijacking. #AACR26
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Source: Ingo Hartung · x.com