Nieves Martinez Lago MD PhD· @DraMartinezLago · X·· 2 days agoScore70
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#ESMO26 🧬 HERIZON-GEA-01 | Phase III
👥 914 pts | 1L HER2+ mGEA
📈 OS, Zani+CT vs Tras+CT:
22.9 vs 19.6 mo (HR 0.76; p=.0088) ✅
🚀 Zani+TIS+CT vs Tras+CT:
27.0 vs 19.6 mo (HR 0.65)
📊 3-year OS: 40% vs 23%
⚠️ TIS addition: HR 0.81 (p=.0502)
💡 New 1L standard: Zani+CT ± TIS!
@OncoAlert @OncobitesTv
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Conference abstracts
LBA79matched by Rapid oral 1: Gastrointestinal tumour, upper digestive
Zanidatamab (zani) + chemotherapy (CT) ± tislelizumab (TIS) for first-line (1L) HER2-positive (HER2+) advanced/metastatic gastroesophageal adenocarcinoma (mGEA): Second interim analysis (IA) from HERIZON-GEA-01
https://esmocongress.esmo.orgSource: Nieves Martinez Lago MD PhD · x.com