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Gaia Griguolo· @GaiaGriguolo · X·· 23 hours agoScore70

KEYNOTE-B49

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KEYNOTE-B49 presented by @hoperugo at #ESMO26

Addition of pembro to CT in PDL1+ HR+HER2- mBC with no previous CT for metastatic BC

✅️primary PFS endpoint reached (curves opening at tails)
✅️higher magnitude of PFS benefit in CPS >=10
❌️no sign OS difference

@OncoAlert

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Conference abstracts
LBA51matched by Proffered paper 2: Breast cancer, early and advanced stage

Results from KEYNOTE-B49: A phase 3, randomized, double-blind study of pembrolizumab (pembro) vs placebo (pbo) plus chemotherapy (CT) in participants (pts) with HR+/HER2− advanced breast cancer (ABC)

https://esmocongress.esmo.org

Source: Gaia Griguolo · x.com

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