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Tom Powles· @tompowles1 · X·· 2 days agoScore90

docetaxel

Body · original

ABBV-969 dual-targeting ADC #ESMO26
MOA = PSMA/STEAP1— TOPO1

Deep responses in metastatic castration-resistant prostate cancer
Surely this one can beat Docetaxel?

2331 views · 46 likes · 18 reposts · 1 reply

Conference abstracts
2300TIPNCT07365995NCT07365995NCT07365995matched by Metastatic prostate cancer

BNT324-03: A phase 3, randomized, open-label trial comparing elfetabart drozuntecan, a B7H3 antibody-drug conjugate, with investigator's choice of docetaxel or cabazitaxel in patients with metastatic castration-resistant prostate cancer

https://esmocongress.esmo.org
LBA15matched by Proffered paper 2: Breast cancer, early and advanced stage

Anbenitamab plus albumin-bound docetaxel in patients (pts) with HER2-positive advanced breast cancer (BC): A randomized phase III study

https://esmocongress.esmo.org
NCT04884282NCT04884282matched by - **标题 / Title:** Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED)

- **标题 / Title:** Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED)

https://esmocongress.esmo.org
Replies in this thread
  1. Raffaele Colombo@raffcolo

    @tompowles1 @OncoAlert But how many patients dosed at above potential RP2D? Most likely those at 10 and 12.5 mg/kg. 8 mg/kg TBD…

Source: Tom Powles · x.com

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