medicalxpress.com· Medical Xpress - Cancer·· 2 days agoPickScore67
Implantable device uses ultrasound to improve drug delivery to the brain
In brief
An MIT team developed LUCID, an implantable device with 24 miniature ultrasound transducers that promote drug spread in the brain. Tissue models and mouse experiments, the latter using an MRI contrast agent, both showed an enlarged distribution range. The system combines local infusion with programmable ultrasound, aims to help drugs bypass the blood-brain barrier, and allows ultrasound dosage to be adjusted via a wireless controller.
Why it matters
The study integrates local infusion with programmable ultrasound in one implantable system and shows wider molecular spread in tissue models and mice.
Source: medicalxpress.com · medicalxpress.com