Nature· Xiaotong Wang·· 20 hours agoPickScore65
Multiancestry conditional and joint analysis applied to GWAS summary statistics
In brief
Manc-COJO is a multiancestry conditional and joint analysis method for GWAS summary statistics. It integrates data from multiple ancestries to identify independent genetic associations, reduces false positives seen in single-ancestry analyses, and supports fast, flexible conditional and joint analysis across diverse populations. The paper was published online in Nature Genetics on 20 October 2026, DOI: 10.1038/s41588-026-02799-1.
Why it matters
It integrates multiancestry GWAS summary statistics into one conditional and joint framework, identifying independent loci and reducing single-ancestry false positives.
Source: Nature