Yakup Ergün· @dr_yakupergun · X·· 1 day agoScore70
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#ESMO26 | VOLGA
Neoadjuvant EV + perioperative durvalumab demonstrated impressive results in MIBC✅
An important detail: Approximately 25% of patients were not cisplatin-ineligible but had refused cisplatin.
Therefore, the potential role of this regimen may extend beyond cisplatin-ineligible patients
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Conference abstracts
LBA2matched by Presidential Symposium I
Perioperative durvalumab with or without tremelimumab plus neoadjuvant enfortumab vedotin in muscle-invasive bladder cancer: Results from the phase 3 VOLGA trial
https://esmocongress.esmo.orgVOLGA
https://esmocongress.esmo.org#ESMO26 | VOLGA | Presidential Symposium-1 In cisplatin-ineligible/refusing MIBC, neoadjuvant EV + perioperative durvalumab significantly improved EFS and OS vs the control arm. EFS: HR 0.55 (24-month: 78% vs 69%) OS: HR 0.58 (24-month: 83% vs 75%) pCR: 45% vs 10% Impressive results! Unlike KEYNOTE-905/EV-303, EV was administered only in the neoadjuvant setting, with no adjuvant EV. I’m looking forward to the discussion during the session.在 X 查看被引用的帖子
Source: Yakup Ergün · x.com