medicalxpress.com· Medical Xpress - Medications·· 22 hours agoPickScore85
Clinical trials generate promising results for improving kidney health
In brief
Three Phase III IgA nephropathy trials were presented at ASN Kidney Week 2026. Atacicept's ORIGIN 3 interim analysis met its primary endpoint and secured FDA accelerated approval, with two-year data showing stabilized eGFR and a markedly reduced progression risk. Sibeprenlimab's VISIONARY trial showed a 97% reduction versus placebo in the risk of kidney function loss or kidney failure over two years, and telitacicept's TELIGAN two-year data confirmed durable kidney protection with a good safety profile in high-risk patients.
Why it matters
The article compiles Phase III data on three APRIL/BLyS inhibitors for IgA nephropathy, allowing readers to compare kidney protection and safety.
Source: medicalxpress.com · medicalxpress.com
