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medicalxpress.com· Medical Xpress - Medications·· 22 hours agoPickScore85

Clinical trials generate promising results for improving kidney health

In brief

Three Phase III IgA nephropathy trials were presented at ASN Kidney Week 2026. Atacicept's ORIGIN 3 interim analysis met its primary endpoint and secured FDA accelerated approval, with two-year data showing stabilized eGFR and a markedly reduced progression risk. Sibeprenlimab's VISIONARY trial showed a 97% reduction versus placebo in the risk of kidney function loss or kidney failure over two years, and telitacicept's TELIGAN two-year data confirmed durable kidney protection with a good safety profile in high-risk patients.

Why it matters

The article compiles Phase III data on three APRIL/BLyS inhibitors for IgA nephropathy, allowing readers to compare kidney protection and safety.

Source: medicalxpress.com · medicalxpress.com

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