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Alan Tan· @alantanmd · X·· 20 hours agoScore70

#PROSTATECANCER

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#ESMO26 PROTEUS discussion by Nicholas van As
• No baseline PSMA PET; enrolled conventionally staged M0
• MFS events: true progression or delayed detection? Most were PSMA PET-detected (8.8% vs 16.3%)
• TTST HR 0.29, but ~20-mo lead-time bias
#ProstateCancer

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  1. Alan Tan@alantanmd

    One year of APA+ADT comes with toxicity, and outcomes after control-arm salvage aren't shown. His view: follow-up too short; would not yet support perioperative APA+ADT with RP in high-risk disease, needing mature survival and post-salvage data first.

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