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Nature Genetics·· 15 hours agoPickScore69

fastGxE is a powerful method for uncovering genotype–environment interactions in biobanks

In brief

fastGxE is a scalable method for analyzing genotype-environment interactions that accelerates genome-wide scans of such interactions in biobank data. Applied to the UK Biobank, it identified previously uncharacterized interaction loci for physical traits and routinely assayed blood biomarkers, revealing context-dependent genetic effects.

Why it matters

fastGxE accelerates genome-wide scans of genotype-environment interactions in biobanks and identifies uncharacterized interaction loci for physical traits and blood biomarkers.

Source: Nature Genetics · nature.com

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