Domino Effect of Glycyrrhizic Acid Epimer Self-Assembly Determines Hydrogel Performance and Biomedical Applications

Penglong Wang's team reports in Angewandte Chemie International Edition that a single C18 chirality inversion between glycyrrhizic acid (GA) and magnesium isoglycyrrhizinate (IGA) triggers cascading differences in self-assembly pathways and the macroscopic properties of their hydrogels.