🔎 New phase III MIBC data at #ESMO26:

Mirrors of Medicine· @mirrorsmed · X·2026-10-23 21:00· 2 days agoScore70

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• KEYNOTE-866: perioperative PEMBRO vs perioperative PBO, plus neoadjuvant GC
• CA017-078: perioperative NIVO vs no treatment, plus neoadjuvant GC
• 📊 Both showed numerically higher pCR, but not statistically significant
• No significant improvement in EFS

💡 Take-home: These data do not support a change in current clinical practice.
#BladderCancer #MIBC

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Conference abstracts

4735Omatched by Proffered paper 1: Genitourinary tumour, renal and urothelial

Perioperative pembrolizumab (pembro) or placebo (pbo) + neoadjuvant cisplatin (cis) and gemcitabine (gem) in participants (pts) with muscle-invasive bladder cancer (MIBC): the double-blind, phase 3 KEYNOTE-866 study

https://esmocongress.esmo.org

Source: Mirrors of Medicine · x.com