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medicalxpress.com· Medical Xpress - Immunology·· 20 hours agoPickScore52

Can psychedelics soothe an overactive immune system? New meta-analysis investigates

In brief

Researchers included 61 studies in a systematic review and meta-analysis and found anti-inflammatory effects reported in 19 of 24 cell studies and 25 of 30 animal studies, with no effect in healthy mice. Only 3 of 10 human trials observed reduced inflammation, and 7 trials did not include patients with active inflammatory disease. Results were published in Brain, Behavior, and Immunity, DOI: 10.1016/j.bbi.2026.107033.

Why it matters

Layered comparison of cell, animal and human evidence shows anti-inflammatory signals mainly in models with elevated inflammation, with few positive human trials.

Source: medicalxpress.com · medicalxpress.com

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