STAT News· Andrew Joseph·· 5 hours agoPickScore83
STAT+: Novartis multiple sclerosis treatment cuts rates of relapse in pivotal trials
In brief
In two Phase 3 trials in relapsing multiple sclerosis, Novartis' remibrutinib reduced the annualized relapse rate by 35.2% and 31.2% compared with Sanofi's Aubagio. Data from REMODEL-1 and REMODEL-2 were presented at MSToronto and published in the Lancet; no Hy's Law cases were seen and rates of elevated liver enzymes were very low.
Why it matters
Both Phase 3 trials disclose relapse reductions and liver safety signals, enabling direct comparison with fenebrutinib on efficacy and safety.
Source: STAT News · statnews.com
