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ilyas sahin, MD· @ilyassahinMD · X·· 1 day agoScore70
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Two more #ESMO26 papers in @NEJM today:

In EGFR-mutated, MET-altered NSCLC progressing on osimertinib, adding savolitinib improved PFS (HR 0.55) and OS (HR 0.68) vs platinum-pemetrexed. 12-month OS was 70% vs 53%.

In previously treated KRAS G12C-mutated NSCLC, divarasib improved median PFS (9.8 vs 5.7 months; HR 0.58) and OS (17.7 vs 12.0 months; HR 0.56) vs sotorasib or adagrasib.

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