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Young Kwang Chae, MD, MPH, MBA· @youngkwangchae · X·· 2026-04-19Score60
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Fascinating #AACR26 talk by Dr. Abu-Remaileh
@DanaFarber

VHL loss → ↑HIF2 → ↑PTHrP in ccRCC
PTHrP drives cachexia + hypercalcemia — tumor-size independent
Belzutifan ↓PTHrP & rescues body composition even WITHOUT tumor shrinkage

@OncoAlert

@OncoAlert

Heat 12 · 8 likes · 1 reply · 3 reposts

Source: Young Kwang Chae, MD, MPH, MBA · x.com

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