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mp.weixin.qq.com· 新药社·· 3 hours agoPickScore77

Hengrui's PD-L1/TGF-βRII Fusion Protein Plus Chemotherapy Extends Overall Survival in Phase 3 RELIGHT Gastric Cancer Trial Published in JCO

中国胃癌患新希望!国产创新药让中位生存期延长4.6个月

In brief

Hengrui Medicine's PD-L1/TGF-βRII bispecific antibody fusion protein relafutafusp alfa (brand name Aizele), combined with chemotherapy as first-line treatment for advanced HER2-negative gastric or gastroesophageal junction adenocarcinoma, has been formally published in the Journal of Clinical Oncology as the phase 3 RELIGHT study.

Why it matters

RELIGHT enrolled 731 patients with HER2-negative advanced gastric cancer, mostly Chinese, providing large randomized controlled data on dual PD-L1/TGF-β pathway blockade in gastric cancer.

Source: mp.weixin.qq.com · mp.weixin.qq.com

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