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Prof. Dr. Ahmet Dirican· @dr_dirican · X·· 23 hours agoScore45

KRAS

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#ESMO2026 | Drugging the Undruggable: A New Era in Precision Oncology

“Undruggable” was never about the target. It was about our tools.

An inspiring presentation by Dr. Vivek Subbiah (@VivekSubbiah) at ESMO 2026, highlighting how previously untargetable cancer drivers are becoming therapeutically actionable.

From KRAS inhibition and p53 reactivation to MYC targeting, protein degradation, synthetic lethality, and AI-driven drug discovery, precision oncology is entering a new era.

The next challenge is not only developing new drugs, but identifying the right molecular target in the right patient.

Comprehensive genomic profiling and ctDNA testing will play an increasingly important role in this transformation.

#ESMO26 @myESMO @VivekSubbiah #PrecisionOncology #UndruggableTargets #KRAS #TP53 #GenomicTesting #LiquidBiopsy @Dr_R_Kurzrock

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Conference abstracts
2683Pmatched by NSCLC, metastatic

First-line (1L) olomorasib + pembrolizumab in KRAS G12C-mutant NSCLC: Updated results from LOXO-RAS-20001 and SUNRAY-01

https://esmocongress.esmo.org

Source: Prof. Dr. Ahmet Dirican · x.com

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