JAMA·· 7 hours agoPickScore61
Pregnancy Outcomes After Living Kidney Donation.
In brief
A Canadian matched cohort study of 385 pregnancies among 252 living kidney donors found that post-donation pregnancy was associated with a higher risk of a composite endpoint of hospitalization for gestational hypertension, preeclampsia, or eclampsia. The composite endpoint occurred in 11.9% of these pregnancies versus 8.3% in matched nondonor pregnancies (RR 1.51, 95% CI 1.10-2.08). Small for gestational age at birth occurred in 13.8% versus 7.9% (RR 1.86, 95% CI 1.37-2.52); most post-donation pregnancies were uncomplicated.
Why it matters
Higher risk of gestational hypertension and other adverse outcomes after living kidney donation can inform prepregnancy counseling of donor candidates and subsequent prenatal care.
Source: JAMA · doi.org