Cell· Chenyang Guan, Seungjin Ryu, Mingze Dong, Yitao Zhu, Rae Maeda, Yun-Hee Youm, Subhasis Mohanty, Hee-Hoon Kim, Lucie Orliaguet, Tamara Dlugos, Steven R. Smith, Eric Ravussin, Janset Onyuru, Hal M. Hoffman, Stephan Siebel, Andrew Wang, Yaqiu Wang, Yuval Kluger, Albert C. Shaw, Thirumala-Devi Kanneganti, Nathan LeBrasseur, Yuki Sugiura, Vishwa Deep Dixit·· 19 hours agoPickScore76
Taurine lowers inflammaging by regulating the NLRP3 inflammasome in macrophages
In brief
Taurine lowers inflammaging by regulating the NLRP3 inflammasome in macrophages. Taurine levels rise with age in both mice and humans; further raising taurine levels in aged mice extends health span and reduces inflammation.
Why it matters
In aged mice, boosting taurine extended health span and linked age-related inflammatory changes to the macrophage NLRP3 inflammasome.
Source: Cell · cell.com